The basic plot is that a company run by Malin Akerman's character is doing genetic experiments on rats in space, to make them essentially invulnerable to anything. The space station blows up, but canisters with the serum being used on the rats end up crashing to Earth and infecting a wolf, alligator, and gorilla. The Gorilla, George, is in a habitat run by Dwayne Johnson's character, who is a primatologist (and because he is 6'5" and 300lbs of muscle, ex-military) who works with George. Naomie Harris plays a scientist who worked for the company on the serum, and Jeffrey Dean Morgan is an FBI agent responding to the Rampaging animals.
The movie is a good blend of action, comedy, and a bit of drama. Of course, it makes The Rock an indestructible hero who can survive getting shot, being in crashing planes and helicopters, and falling buildings, and not only walk away but keep fighting. So, in that way, the movie is clearly tongue-in-cheek. The Rock also continues to show that he is a decent comedic actor and an excellent action star. And he can be self-deprecating and does not seem to take himself too seriously.
The 4k set is a two-disc set containing a UHD disc and a regular Blu-Ray disc. The film looks and sounds great in UHD, especially with a large screen. All the extras are included on the second, regular, Blu-Ray disc. Those include several behind-the-scenes and making-of featurettes (averaging about 10 minutes long), as well as a short gag reel. There is around an hour, give or take, of extras. Overall, it is an enjoyable action movie if you can suspend your disbelief and not take it extremely seriously. If you are a fan of The Rock's films, especially the newer ones like San Andreas or Hobbs and Shaw, then you will very likely enjoy this. If you are not a big fan of action movies as a whole, especially ones with lots of explosions and monsters, then this is not going to do anything for you.