There are essentially two storylines that run in parallel with each other during the movie. The first is Wade's origin story includes his sex-worker girlfriend Vanessa (played by Firefly and Gotham alum Morena Baccarin), and TJ Miller, as Deadpool's buddy Weasel. Miller steals many a scene he is in, which is no small feat with Deadpool throwing out zingers every couple of seconds. The second is the revenge story, which is where all of the action in the movie takes place. Of course, the storylines do intersect at the end.
For those who get the blu-ray, the movie looks and sounds wonderful in HD. The extras include two separate commentary tracks, deleted scenes, a gag reel, an image gallery, videos that were a part of the movie's promotional campaign, and the most extensive extra, an hour and twenty-minute long making-of documentary (that is split into five parts).
Overall, the movie is awesome. The jokes are great, and make fun of everything from Reynold's acting ability vs. his looks, the horrible incarnation of Deadpool in X-Men Origins: Wolverine (also played by Reynolds), as well as the Green Lantern movie (also starring Reynolds). It seems that everyone in the cast was having a blast and not taking themselves too seriously. It is most definitely not a family-friendly movie as there is a lot of swearing and sexual jokes. The action is great, especially the battle at the end, and the movie has no problem lampooning the superhero genre. It is definitely worth checking out.